Reduced Operations During Harvard Winter Recess

The SBDB will be operating at a reduced level between Dec 26 2025 and Jan 1 2026 due to Harvard Winter Recess. Deposition credential requests and dataset release requests during this time will be handled following this time period.




Datasets from the Yale University School of Medicine



X-Ray Diffraction data from Catalytic domain of MEKK2, source of 9P6A structure

Two native datasets from one crystal were merged together by rescaling using XSCALE.

X-Ray Diffraction data from c-Src SH3 domain, source of 9OFX structure

X-Ray Diffraction data for c-Src SH3 domain

X-Ray Diffraction data from SHP2 tandem SH2 domains in complex with PZR doubly tyrosine phosphorylated ITIM peptide, source of 9MQ5 structure

X-ray diffraction images

X-Ray Diffraction data from Human p120RasGAP, C2 and GAP domains, source of 9BZ4 structure

Native datasets

X-Ray Diffraction data from LIMK2, source of 8GI4 structure

4 sweeps

X-Ray Diffraction data from p120RasGAP SH2-SH3-SH2 in complex with p190RhoGAP doubly phosphorylated peptide, source of 8DGQ structure

Four sweeps

X-Ray Diffraction data from p120RasGAP SH3 domain in complex with DLC1 GAP domain, source of 7TPB structure

Two sweeps, native

X-Ray Diffraction data from Integrin beta5(743-774)-linker-PAK4cat(D440N/S474E), source of 7S47 structure

Native data

X-Ray Diffraction data from PAK4cat in complex with Integrin beta5 760-770 peptide, source of 7S48 structure

Native data

X-Ray Diffraction data from PAK4cat (D440N/S474E) in complex with Integrin beta5 760-770 peptide, source of 7S46 structure

Native datasets

X-Ray Diffraction data from PAK4 kinase domain in complex with LIMK1 Thr508 substrate peptide, source of 6WLY structure

Native dataset

X-Ray Diffraction data from PAK4 kinase domain in complex with beta-catenin Ser675 substrate peptide, source of 6WLX structure

Native data

X-Ray Diffraction data from p120RasGAP C-terminal SH2 domain with p190RhoGAP pTyr-1087 peptide, source of 6WAY structure

X-Ray Diffraction data from p120RasGAP C-terminal SH2 domain with p190RhoGAP pTyr-1087 peptide

X-Ray Diffraction data from p120RasGAP C-terminal SH2 domain, source of 6WAX structure

X-Ray Diffraction data from p120RasGAP C-terminal SH2 domain

X-Ray Diffraction data from p120RasGAP N-terminal SH2 domain with p190RhoGAP pTyr-1105 peptide, source of 6PXC structure

Native data. 3 passes.

X-Ray Diffraction data from p120RasGAP N-terminal SH2 domain, source of 6PXB structure

Native data. 2 passes.

X-Ray Diffraction data from p190RhoGAP-A N-GTPase domain, source of 6D4G structure

8 sweeps

X-Ray Diffraction data from CCM2 HHD in complex with MEKK3 NPB1, source of 4Y5O structure

Native

X-Ray Diffraction data from CCM2 PTB domain in complex with KRIT1 NPxY/F3, source of 4WJ7 structure

Native

X-Ray Diffraction data from Crystal structure of the CCM2 C-terminal Harmonin Homology Domain (HHD), source of 4FQN structure

Native

X-Ray Diffraction data from CCM3 in complex with CCM2 LD-like motif, source of 4TVQ structure

Native

X-Ray Diffraction data from Co-crystal structure of Rap1 in complex with KRIT1, source of 4DXA structure

Native

X-Ray Diffraction data from PINCH2 LIM2 in complex with ILK ankyrin repeat domain, source of 3IXE structure

Native

X-Ray Diffraction data from Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain, source of 3F6Q structure

Iodide soak

X-Ray Diffraction data from Lysozyme facilitates crystallization of a hetero-trimeric Cortactin:Arg:Lysozyme complex, source of 3ULR structure

Native

X-Ray Diffraction data from Crystal structure of Arg SH2 domain, source of 4EIH structure

Native

X-Ray Diffraction data from ICAP1 in complex with integrin beta 1 cytoplasmic tail, source of 4DX9 structure

Se SAD

X-Ray Diffraction data from ICAP1 in complex with KRIT1 N-terminus, source of 4DX8 structure

Native

X-Ray Diffraction data from Co-crystal structure of ICAP1 PTB domain in complex with a KRIT1 peptide, source of 4JIF structure

Native

X-Ray Diffraction data from PAK4cat-PAK4N45-CDC42, source of 5UPK structure

Diffaction images

X-Ray Diffraction data from PAK4FL-CDC42, source of 5UPL structure

Diffaction images

X-Ray Diffraction data from PEAK1 (Sugen Kinase 269, SgK269), source of 6BHC structure

360 images

X-Ray Diffraction data from PAK4, source of 5VEF structure

2 180 degree sweeps

X-Ray Diffraction data from PAK4, source of 5VEE structure

2 180 degree sweeps

X-Ray Diffraction data from PAK4, source of 5VED structure

180 degrees

X-Ray Diffraction data from p190RhoGAP pseudoGTPase, source of 5U4V structure

Native dataset

X-Ray Diffraction data from p190RhoGAP pseudoGTPase domain, source of 5U4U structure

Native datasets

X-Ray Diffraction data from human Tie2 FNIII domains, source of 5UTK structure

Selenomethionine labelled Tie2 FNIIIa–c collected at the remote wavelength

X-Ray Diffraction data from PAK4 F461V with PAKtide-S, source of 4JDK structure

X-ray diffraction

X-Ray Diffraction data from PAK4 F461V with PAKtide-T, source of 4JDJ structure

X-ray diffraction

X-Ray Diffraction data from PAK4 with PAKtide-T, source of 4JDH structure

X-ray diffraction

X-Ray Diffraction data from PAK4 with PAKtide-S, source of 4JDI structure

X-ray diffraction

X-Ray Diffraction data from PAK4 with RPKPLVDP, source of 4FII structure

X-ray diffraction

X-Ray Diffraction data from PAK4 with QKFTGLPRQW, source of 4FIH structure

X-ray diffraction

X-Ray Diffraction data from PAK4 with RPKPLVDP, source of 4FIF structure

X-ray diffraction

X-Ray Diffraction data from PAK4, source of 4FIG structure

X-ray diffraction

X-Ray Diffraction data from PAK4 FL, source of 4FIE structure

X-ray diffraction

X-Ray Diffraction data from PAK4, source of 4FIJ structure

X-ray diffraction

X-Ray Diffraction data from KRIT1 ARD-FERM, source of 5D68 structure

180°, 1° oscillations.

X-Ray Diffraction data from RT52A (recombinant HIV reverse transcriptase) from E. coli, source of 5C25 structure

Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 6-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-5,7-dimethyl-2-naphthonitrile (JLJ639), a Non-nucleoside Inhibitor. 180 x 1 degree images collected for processing. Native data set collected on 24-ID-E at APS

X-Ray Diffraction data from human KIT D4D5 harboring oncogenic mutation T417I, Δ418,419, source of 4PGZ structure

native dataset

X-Ray Diffraction data from human KIT D4D5 in complex with Fab19, source of 4K94 structure

native dataset

X-Ray Diffraction data from human KIT D4D5 in complex with Fab79D, source of 4K9E structure

Native data set

X-Ray Diffraction data from RT52A (recombinant HIV reverse transcriptase) from E. coli, source of 4LSL structure

Crystal Structure of HIV-1 Reverse Transcriptase in Complex with (E)-3-(3-(4-chloro-2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ476), a non-nucleoside inhibitor. 180 x 1 degree images collected for processing. Native data set collected on X29A at NSLS-I.

X-Ray Diffraction data from SNX17 FERM domain with KRIT1 NPxY/F2, source of 4TKN structure

Native