Notice

The SBDB will be operating at a reduce level due to maintance.

The SBDB will be operating at a reduced level Tue 06/18/2019 between 1PM and 5PM due to underlying maintance.

X-Ray Diffraction data from M2 muscarinic acetylcholine receptor, source of 4MQT structure

Data DOI: 10.15785/SBGRID/125 | ID: 125

Publication DOI: 10.1038/nature12735

4MQT Coordinates: Viewer, PDB (RCSB) (PDBe), MMDB

Kruse Laboratory, Harvard Medical School

Release Date: May 21, 2015

Data Access Instructions

1. If this dataset is locally available, it should be accessable at /programs/datagrid/125

2. To download this dataset, please run the following command from your Terminal on a Linux or OS X workstation:

'rsync -av rsync://data.sbgrid.org/10.15785/SBGRID/125 .' (Harvard Medical School, USA)

Depending on your location, faster access may be available from a Tier 1 site closer to your location

'rsync -av rsync://sbgrid.icm.uu.se/10.15785/SBGRID/125 .' (Uppsala University, Sweden)

'rsync -av rsync://sbgrid.pasteur.edu.uy/10.15785/SBGRID/125 .' (Institut Pasteur de Montevideo, Uruguay)

'rsync -av rsync://sbgrid.ncpss.org/10.15785/SBGRID/125 .' (Shanghai Institutes for Biological Sciences, China)

3. After the transfer is completed, please issue the following command to verify data integrity:

'cd 125 ; shasum -c files.sha'

Storage requirements: 2.6G

Biological Sample:

M2 muscarinic acetylcholine receptor

Dataset Type:

X-Ray Diffraction

Subject Composition:

Protein

Collection Facility:

APS GM/CA 23ID-D

Data Creation Date:

April 16, 2013

Related Datasets:

None


Cite this Dataset

Kruse, A. 2015. "X-Ray Diffraction data for: M2 muscarinic acetylcholine receptor. PDB Code 4MQT", SBGrid Data Bank, V1, https://doi.org/10.15785/SBGRID/125.

Download Citation

Dataset Description

This dataset is compiled from 18 crystals of M2 receptor grown in the presence of the agonist iperoxo and the allosteric modulator LY2119620.

Project Members

Name Additional Roles Affiliation While Working on the Project
Andrew KruseData Collector, DepositorStanford University
Andrew KrusePIHarvard Medical School

Reprocessing Instructions

The following wedges were processed: AK_E16_b_3_* Frames 1 to 5 AK_E16_l_3_* Frames 1 to 5 AK_F2_e1_1_* Frames 1 to 5 AK_F6_g_3_* Frames 1 to 5 AK_F6_g2_3_* Frames 1 to 3 (this is the same crystal as AK_F6_g_3_*) AK_F6_h_3_* Frames 1 to 5 AK_F6_j_3_* Frames 1 to 5 AK_E16_k_3_* Frames 1 to 5 AK_E16_l_3_* Frames 1 to 5 AK_F4_a_3_* Frames 1 to 5 AK_F1_a_1_* Frames 1 to 5 AK_F6_j_3_* Frames 1 to 5 AK_F6_l_3_* Frames 1 to 5 AK_F6_m_3_* Frames 1 to 5 AK_E16_a_3_* Frames 1 to 5 AK_E16_g_3_* Frames 1 to 5 AK_E16_h_3_* Frames 1 to 5 AK_F1_a_4_* Frames 1 to 5 AK_F1_a_7_* Frames 1 to 3

This dataset is part of the SBDB Pilot Reference Collection, and has processed intensities available from that collection.

License and Terms of use

License: CC0

Terms: Our Community Norms as well as good scientific practices expect that proper credit is given via citation. Please use the data citation, as generated by the SBGrid Data Bank.